Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230507 | 0.92 | PCSK9 (0.48) | ADORA2AADORA1TLR7ADORA3TRPV1 | |
| SCHEMBL18230317 | 0.92 | ADORA2A (0.48) | ADORA2AADORA1ADORA3TRPV1TRPV4 | |
| SCHEMBL18230296 | 0.89 | TRPV1 (0.54) | ADORA2AADORA1TLR7ADORA3TRPV1 | |
| SCHEMBL18230411 | 0.88 | ADORA3 (0.61) | ADORA2AADORA1ADORA3TRPV4ALDH1A1 | |
| SCHEMBL18230512 | 0.87 | GRM1 (0.53) | ADORA2AADORA1ADORA3TRPV4GRM1 | |
| SCHEMBL18230271 | 0.87 | NOX1 (0.40) | ADORA2AADORA1TLR7ADORA3TRPV4 | |
| SCHEMBL18230432 | 0.86 | ADORA3 (0.46) | ADORA2AADORA1TLR7ADORA3TRPV4 | |
| SCHEMBL18230519 | 0.86 | ADORA1 (0.65) | ADORA2AADORA1TLR7ADORA3MTOR | |
| SCHEMBL18230427 | 0.86 | ADORA1 (0.54) | ADORA2AADORA1TLR7ADORA3MTOR | |
| SCHEMBL18230364 | 0.85 | ADORA2A (0.42) | ADORA2AADORA1ADORA3TRPV4GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |