Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230409 | 0.87 | ADORA2A (0.50) | GRM1ADORA2AADORA1HTTADORA3 | |
| SCHEMBL18230411 | 0.87 | ADORA3 (0.61) | ADORA2AADORA1NPC1KDM4ERAB9A | |
| SCHEMBL18230317 | 0.85 | ADORA2A (0.48) | GRM1ADORA2AADORA1KDM4EHTT | |
| SCHEMBL18230296 | 0.84 | TRPV1 (0.54) | GRM1ADORA2AADORA1KDM4EHTT | |
| SCHEMBL18230294 | 0.82 | TRPV1 (0.54) | GRM1ADORA2AADORA1NPC1KDM4E | |
| SCHEMBL18230448 | 0.81 | ADORA2A (0.54) | GRM1ADORA2AADORA1NPC1KDM4E | |
| SCHEMBL18230392 | 0.81 | ADORA3 (0.51) | GRM1ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL18230507 | 0.80 | PCSK9 (0.48) | ADORA2AADORA1NPC1RAB9AADORA3 | |
| SCHEMBL18230503 | 0.79 | ADORA2A (0.45) | GRM1ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL18230312 | 0.79 | GCK (0.55) | GRM1ADORA2AADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |