Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230494 | 0.89 | NPC1 (0.49) | TRPV4RAB9AMAPTL3MBTL1LMNA | |
| SCHEMBL18230507 | 0.87 | PCSK9 (0.48) | TRPV4ADORA2AADORA1ADORA3RAB9A | |
| SCHEMBL18230409 | 0.87 | ADORA2A (0.50) | TRPV4ADORA2AADORA1ADORA3MAPT | |
| SCHEMBL18230364 | 0.84 | ADORA2A (0.42) | TRPV4ADORA2AADORA1ADORA3RAB9A | |
| SCHEMBL18230353 | 0.81 | PTGES (0.49) | TRPV4ADORA2AADORA1ADORA3RAB9A | |
| SCHEMBL18230342 | 0.80 | ADORA2A (0.44) | TRPV4ADORA2AADORA1ADORA3MAPT | |
| SCHEMBL18230317 | 0.79 | ADORA2A (0.48) | TRPV4ADORA2AADORA1ADORA3MAPT | |
| SCHEMBL18094514 | 0.79 | THRB (0.45) | NOX1ADORA3MAPTTLR7THRB | |
| SCHEMBL18230432 | 0.78 | ADORA3 (0.46) | TRPV4ADORA2AADORA1ADORA3MAPT | |
| SCHEMBL18230284 | 0.77 | ADORA2A (0.39) | TRPV4ADORA2AADORA1ADORA3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |