Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4B | O94953 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLTP | P55058 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230296 | 0.84 | TRPV1 (0.54) | ADORA2AADORA1ADORA3KDM4AKDM4B | |
| SCHEMBL18230294 | 0.84 | TRPV1 (0.54) | ADORA2AADORA1ADORA3KDM4AKDM4B | |
| SCHEMBL18230411 | 0.84 | ADORA3 (0.61) | ADORA2AADORA1ADORA3MEN1KMT2A | |
| SCHEMBL19638116 | 0.83 | ADORA2A (0.54) | ADORA2AADORA1ADORA3KDM4AKDM4B | |
| SCHEMBL18230409 | 0.82 | ADORA2A (0.50) | ADORA2AADORA1ADORA3KDM4AKDM4B | |
| SCHEMBL18230423 | 0.82 | ADORA3 (0.61) | ADORA2AADORA1ADORA3KDM4AKDM4B | |
| SCHEMBL30309324 | 0.82 | ADORA2A (0.49) | ADORA2AADORA1ADORA3MEN1KMT2A | |
| SCHEMBL22331534 | 0.82 | ADORA2A (0.49) | ADORA2AADORA1ADORA3MEN1KMT2A | |
| SCHEMBL18230414 | 0.81 | ADORA2A (0.51) | ADORA2AADORA1ADORA3KDM4AKDM4B | |
| SCHEMBL18230512 | 0.81 | GRM1 (0.53) | ADORA2AADORA1ADORA3KDM4AKDM4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |