SCHEMBL182305

SCHEMBL182305

C=C(CCCC)C(=O)C(=C)CCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.52
CES2 O00748 5/20 0.52
ALDH1A1 P00352 4/20 0.48
TP53 P04637 1/20 0.48
CA1 P00915 1/20 0.46
AKR1B1 P15121 1/20 0.42
PPARG P37231 6/20 0.40
PPARD Q03181 6/20 0.40
PPARA Q07869 6/20 0.40
GPR84 Q9NQS5 5/20 0.40
HDAC11 Q96DB2 5/20 0.40
TSHR P16473 4/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
PTPN1 P18031 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
MEN1 O00255 1/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11270109 0.92 CES2 (0.55) CES1CES2ALDH1A1AKR1B1PPARG
SCHEMBL182418 0.90 CES2 (0.56) CES1CES2ALDH1A1AKR1B1PPARG
SCHEMBL11511121 0.90 CES2 (0.56) CES1CES2ALDH1A1AKR1B1PPARG
SCHEMBL8719599 0.90 CES2 (0.56) CES1CES2ALDH1A1AKR1B1PPARG
SCHEMBL17635459 0.87 CES1 (0.46) CES1CES2ALDH1A1TP53CA1
SCHEMBL13447284 0.85 CES1 (0.39) CES1CES2ALDH1A1TP53CA1
SCHEMBL2128300 0.82 CES2 (0.47) CES1CES2ALDH1A1TP53AKR1B1
SCHEMBL1353582 0.82 CES1 (0.47) CES1CES2ALDH1A1TP53CA1
SCHEMBL6916130 0.81 CES1 (0.50) CES1CES2ALDH1A1TP53CA1
SCHEMBL22623 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001068726-A1 ATOM TRANSFER RADICAL POLYMERISATION CATALYST BP CHEMICALS LIMITED (GB) 2001-09-20 WO claimed
US-12630751-B2 Two stage methods for processing adhesives and related compositions AVERY DENNISON CORPORATION (US) 2026-05-19 US disclosed
EP-3898810-B1 ADHESIVE WITH HIGH FILLER CONTENT AVERY DENNISON CORP (US) 2025-12-03 EP disclosed
US-12312518-B2 Adhesive with high filler content AVERY DENNISON CORPORATION (US) 2025-05-27 US disclosed
US-12304988-B2 Acrylic polymers having controlled placement of functional groups AVERY DENNISON CORPORATION (US) 2025-05-20 US disclosed
US-12163069-B2 Post-polymerization functionalization of pendant functional groups AVERY DENNISON CORPORATION (US) 2024-12-10 US disclosed
EP-3739010-B1 TWO STAGE METHODS FOR PROCESSING ADHESIVES AND RELATED COMPOSITIONS AVERY DENNISON CORP (US) 2024-09-04 EP disclosed
US-12065588-B2 Two stage methods for processing adhesives and related compositions AVERY DENNISON CORPORATION (US) 2024-08-20 US disclosed
US-20240263055-A1 Two Stage Methods for Processing Adhesives and Related Compositions AVERY DENNISON CORPORATION 2024-08-08 US disclosed
EP-3289037-B1 ACRYLIC EMULSION ADHESIVES AVERY DENNISON CORP (US) 2023-10-25 EP disclosed
WO-1999058578-A1 POLYMERISATION CATALYST BP CHEMICALS LIMITED (GB) 1999-11-18 WO disclosed
US-5886118-A ACTIVATING THE ADDITIONAL HOMO- OR COPOLYMERIZATION IN SOLVENT AND A METAL CATALYST WITH AN INITIATOR SELECTED FROM THE GROUP CONSISTING OF SULFONYL HALIDES, HALOPROPIONITRILES, MONOADDUCTS DERIVED FROM SULFONYL HALIDES AND ACRYLONITRILE CASE WESTERN RESERVE UNIVERSITY (US) 1999-03-23 US disclosed
EP-0872493-A2 Process for polymerizing acrylonitrile Case Western Reserve University (US) 1998-10-21 EP disclosed
US-4395446-A Peelable adhesive structure TOYO SEIKAN KAISHA, LTD. (JP) 1983-07-26 US disclosed
US-4370190-A PAINTS, MODIFIED OLEFIN POLYMER, MULTILAYER TOYO SEIKAN KAISHA, LTD. (JP) 1983-01-25 US disclosed
US-4284775-A 1,4-Diazabicyclooctane di-N,N'-quaternized compounds THE UPJOHN COMPANY (US) 1981-08-18 US disclosed
US-4269321-A CROWN OR CAP CLOSURES TOYO SEIKAN KAISHA, LTD. (JP) 1981-05-26 US disclosed
US-4232086-A PROTECTIVE COATINGS TOYO SEIKAN KAISHA, LTD. (JP) 1980-11-04 US disclosed
US-4224379-A Peelable bonded structures and process for preparing same TOYO SEIKAN KAISHA, LTD. (JP) 1980-09-23 US disclosed
US-4216322-A Process for making triethylene diamines THE UPJOHN COMPANY (US) 1980-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630751-B2 Two stage methods for processing adhesives and related compositions CDH1, ITGB2, ITGA2B CES1 4480/4885CES2 2615/4885ALDH1A1 2071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.