Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.61 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333061 | 0.86 | TBXAS1 (0.78) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL29403620 | 0.86 | TBXAS1 (0.78) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL27446829 | 0.85 | TBXAS1 (0.76) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL305976 | 0.85 | TBXAS1 (0.79) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL18230749 | 0.82 | ALDH1A1 (0.46) | TBXAS1RECQLKDM4EALDH1A1LMNA | |
| P-Xylene SCHEMBL6281558 | 0.79 | TBXAS1 (0.68) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL27502761 | 0.79 | TBXAS1 (0.68) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL83186 | 0.78 | RECQL (0.62) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| O-Xylene SCHEMBL6281561 | 0.78 | TBXAS1 (0.66) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 | |
| SCHEMBL30861827 | 0.77 | TBXAS1 (0.57) | TBXAS1NAPRTFFAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294296-A1 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | Medibeacon Inc. (US) | 2018-03-21 | — | — | EP | disclosed |
| WO-2016183351-A1 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | MEDIBEACON INC. (US) | 2016-11-17 | — | — | WO | disclosed |