Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660224 | 0.88 | PKM (0.60) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL2566762 | 0.88 | PKM (0.60) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL7384333 | 0.82 | CYP1A2 (0.62) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL2433129 | 0.81 | PKM (0.58) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL11062758 | 0.79 | TBXAS1 (0.71) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL9385322 | 0.77 | TBXAS1 (0.56) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL5051173 | 0.75 | PKM (0.49) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL21896075 | 0.75 | TBXAS1 (0.56) | PKMKMT2ATBXAS1ANPEPERAP1 | |
| SCHEMBL18230747 | 0.75 | TBXAS1 (0.61) | TBXAS1KDM4ECYP1A2NAPRTRECQL | |
| SCHEMBL6900349 | 0.74 | ANPEP (0.54) | TBXAS1ANPEPERAP1ERAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294296-A1 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | Medibeacon Inc. (US) | 2018-03-21 | — | — | EP | disclosed |
| WO-2016183351-A1 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | MEDIBEACON INC. (US) | 2016-11-17 | — | — | WO | disclosed |