Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 16/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 15/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615428 | 0.87 | SPHK1 (0.43) | SPHK2SPHK1CD274PDCD1MCHR1 | |
| SCHEMBL1823764 | 0.84 | GAA (0.39) | MCHR1 | |
| SCHEMBL1824155 | 0.83 | KDM4E (0.42) | — | |
| SCHEMBL1828535 | 0.82 | GAA (0.47) | — | |
| SCHEMBL1824756 | 0.81 | CXCR4 (0.41) | — | |
| SCHEMBL1825695 | 0.79 | PARP1 (0.44) | — | |
| SCHEMBL1825597 | 0.78 | TUBB4A (0.42) | — | |
| SCHEMBL1826204 | 0.76 | MCHR2 (0.38) | — | |
| SCHEMBL1823810 | 0.76 | ALDH1A1 (0.43) | — | |
| SCHEMBL1825063 | 0.76 | TUBB4A (0.43) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-B1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2011-05-04 | — | — | EP | claimed |