Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824155 | 0.88 | KDM4E (0.42) | KMT2ACYP2C9KDM4EALDH1A1HPGD | |
| SCHEMBL1616243 | 0.87 | GAA (0.49) | GAALTA4HICAM1LMNAKMT2A | |
| SCHEMBL1823764 | 0.83 | GAA (0.39) | GAALTA4HKMT2AMAPTKDM4E | |
| SCHEMBL1824756 | 0.83 | CXCR4 (0.41) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL1825695 | 0.82 | PARP1 (0.44) | GAALMNAL3MBTL1MAPTKDM4E | |
| SCHEMBL1823170 | 0.82 | SPHK2 (0.43) | — | |
| SCHEMBL1823810 | 0.79 | ALDH1A1 (0.43) | GAALMNAKMT2ACYP3A4NPSR1 | |
| SCHEMBL1826204 | 0.79 | MCHR2 (0.38) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1821784 | 0.78 | FAAH (0.37) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1826566 | 0.78 | DRD4 (0.44) | GAALMNAL3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-B1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2011-05-04 | — | — | EP | claimed |