Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179246 | 0.87 | MEN1 (0.49) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL11181615 | 0.84 | ALDH1A1 (0.43) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL5507988 | 0.84 | KDM4E (0.46) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL10863551 | 0.84 | KDM4E (0.46) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL9765502 | 0.83 | ALDH1A1 (0.52) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL11465112 | 0.82 | KDM4E (0.42) | GPR84ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL184768 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL9765561 | 0.81 | KDM4E (0.44) | ALDH1A1CYP1B1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2300244 | 0.79 | ALDH1A1 (0.56) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL9765551 | 0.79 | HPRT1 (0.44) | ALDH1A1HSD17B10AKR1B1MAPK14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122260-A2 | INHIBITORS OF SARS-COV-2 | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2023-06-29 | — | — | WO | disclosed |
| US-10476006-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-12 | — | — | US | disclosed |
| EP-3281936-B1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| EP-3281936-B1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| EP-3281936-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | Nichem Fine Technology Co., Ltd. (TW) | 2018-02-14 | — | — | EP | disclosed |
| EP-3281936-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | Nichem Fine Technology Co., Ltd. (TW) | 2018-02-14 | — | — | EP | disclosed |
| US-20170000749-A1 | Methods for Treating Cognitive Disorders Using Inhibitors of Histone Deacetylase | FMR LLC | 2017-01-05 | — | — | US | disclosed |
| US-20170000749-A1 | Methods for Treating Cognitive Disorders Using Inhibitors of Histone Deacetylase | FMR LLC | 2017-01-05 | — | — | US | disclosed |
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |
| EP-0035711-B1 | 10-SUBSTITUTED-5-CYANOMETHYLENE-DIBENZO-(A,D)CYCLOHEPTENES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1984-05-09 | — | — | EP | disclosed |
| US-4447610-A | SEDATIVES, TRANQUILIZERS, NEUROLEPTIC AGENTS, MUSCLE RELAXANTS AND ANTIDEPRESSANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | disclosed |
| EP-0019866-B1 | PROCESS FOR THE PREPARATION OF 10,11-DIHYDRO-5H-DIBENZO (A,D)CYCLOHEPTEN-5,10-IMINES | MERCK & CO. INC. (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4399141-A | 5-Alkyl or hydroxyalkyl substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines and anticonvulsant use thereof | MERCK & CO., INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0035711-A2 | 10-Substituted-5-cyanomethylene-dibenzo-(a,d)cycloheptenes, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4048223-A | 3-Dimethylsulfamoyl-5-[amino(alkyl or alkylidene)]-5H-dibenzo [a,d]cycloheptenes | MERCK & CO., INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3981917-A | Chemical compounds | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3978121-A | 5H Dibenzo[a,d]cycloheptene derivatives | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10476006-B2 | Compound and organic electronic device using the same | ESR1, AOC2, PIEZO1 | GPR84 4218/4885ALDH1A1 71/4885HSD17B10 2056/4885 |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | ESR1, AOC2, PIEZO1 | GPR84 4218/4885ALDH1A1 71/4885HSD17B10 2056/4885 |
| US-20170000749-A1 | Methods for Treating Cognitive Disorders Using Inhibitors of Histone Deacetylase | HDAC5, KAT2A, HDAC1 | GPR84 3518/4885ALDH1A1 1086/4885HSD17B10 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.