Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 8/20 | 0.41 |
| ▸ | CDC25A | P30304 | 8/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 5/20 | 0.41 |
| ▸ | S100A4 | P26447 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16297128 | 0.82 | LMNA (0.77) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| SCHEMBL19628263 | 0.75 | ALDH1A1 (0.67) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| SCHEMBL16296919 | 0.75 | LMNA (1.00) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| SCHEMBL16297214 | 0.74 | KMT2A (0.65) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| SCHEMBL7952246 | 0.70 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| SCHEMBL4784115 | 0.69 | PTPRC (0.50) | ALDH1A1LMNAKMT2AL3MBTL1NSD2 | |
| SCHEMBL16297131 | 0.69 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| SCHEMBL16296768 | 0.69 | HSP90AA1 (0.57) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| SCHEMBL5420918 | 0.68 | KMT2A (0.57) | ALDH1A1LMNAKMT2AL3MBTL1MITF | |
| Anthraquinone SCHEMBL11789994 | 0.68 | KMT2A (0.56) | ALDH1A1LMNAKMT2AL3MBTL1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055142-A2 | 1,4-QUINONES AND THEIR SULFUR ANALOGUES USEFUL AS LIGANDS OF N-ACETYLTRANSFERASES | ISIS INNOVATION LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |