Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615897 | 0.87 | PTGS2 (0.40) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1822948 | 0.86 | MEN1 (0.41) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1825505 | 0.85 | ALDH1A1 (0.40) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1824983 | 0.84 | CYP2C9 (0.41) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1826051 | 0.84 | TP53 (0.36) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1826130 | 0.84 | TP53 (0.44) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1822442 | 0.81 | TP53 (0.42) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1826315 | 0.81 | TP53 (0.42) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1824783 | 0.80 | MAPT (0.44) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1823959 | 0.80 | TP53 (0.48) | MAPTTP53POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-B1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2011-05-04 | — | — | EP | claimed |