SCHEMBL18235846

SCHEMBL18235846

CCCCC(=O)O/N=C(/C)C(=O)c1ccc2c(c1)C(CC)(CC)c1ccccc1-2

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 11/20 0.37
▸ KMT2A Q03164 4/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ TDP1 Q9NUW8 4/20 0.34
▸ L3MBTL1 Q9Y468 4/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ RECQL P46063 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18235851 0.97 KMT2A (0.39) PDK2KMT2AMEN1TDP1L3MBTL1
SCHEMBL18235844 0.96 KMT2A (0.39) PDK2KMT2AMEN1TDP1L3MBTL1
SCHEMBL18235862 0.94 PDK2 (0.36) PDK2KMT2AL3MBTL1ALDH1A1
SCHEMBL18235859 0.93 APEX1 (0.37) PDK2KMT2AMEN1TDP1L3MBTL1
SCHEMBL18235856 0.90 KMT2A (0.39) PDK2KMT2AMEN1TDP1L3MBTL1
SCHEMBL18235845 0.89 PDK2 (0.38) PDK2KMT2AL3MBTL1
SCHEMBL20032516 0.89 PDK2 (0.38) PDK2KMT2AL3MBTL1
SCHEMBL18235858 0.89 KMT2A (0.38) PDK2KMT2AMEN1TDP1L3MBTL1
SCHEMBL18235865 0.89 APEX1 (0.37) PDK2KMT2AMEN1TDP1L3MBTL1
SCHEMBL18235849 0.89 PDK2 (0.37) PDK2KMT2AMEN1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9873663-B2 Fluorenyl β-oxime ester compounds, photopolymerization initiator and photoresist composition containing the same SAMYANG CORPORATION (KR) 2018-01-23 — — US disclosed
US-9873663-B2 Fluorenyl β-oxime ester compounds, photopolymerization initiator and photoresist composition containing the same SAMYANG CORPORATION (KR) 2018-01-23 — — US disclosed
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME SAMYANG CORPORATION (KR) 2016-11-17 — — US disclosed
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME SAMYANG CORPORATION (KR) 2016-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME PPOX, FTO, PFAS PDK2 981/4885KMT2A 725/4885MEN1 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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