Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824576 | 0.88 | KMT2A (0.46) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL3582246 | 0.84 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1823656 | 0.84 | THRB (0.44) | KMT2AMEN1SMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL1827975 | 0.83 | KMT2A (0.40) | KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL7824324 | 0.82 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL1824593 | 0.82 | KMT2A (0.44) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL1827614 | 0.79 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2NPSR1RXFP1ALDH1A1 | |
| SCHEMBL15654637 | 0.77 | CYP26A1 (0.58) | SMN1; SMN2ALDH1A1CTSAPOLB | |
| SCHEMBL3781378 | 0.77 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2851129 | 0.77 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |