Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CTSA | P10619 | 3/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582402 | 0.84 | GPR88 (0.63) | KMT2AMEN1NPSR1ACACBGPR88 | |
| SCHEMBL7733340 | 0.84 | FAAH (0.60) | KMT2AMEN1NPSR1ACACBGPR88 | |
| SCHEMBL1823903 | 0.82 | KMT2A (0.46) | KMT2AMEN1ALDH1A1THRBHPGD | |
| SCHEMBL15654637 | 0.82 | CYP26A1 (0.58) | ALDH1A1CTSACYP26A1SMN1; SMN2POLB | |
| SCHEMBL3781378 | 0.82 | KMT2A (0.47) | KMT2AMEN1CYP26A1SMN1; SMN2 | |
| SCHEMBL3375103 | 0.82 | KMT2A (0.58) | KMT2AMEN1ALDH1A1CYP26A1SMN1; SMN2 | |
| SCHEMBL640977 | 0.82 | KMT2A (0.58) | KMT2AMEN1ALDH1A1CYP26A1SMN1; SMN2 | |
| SCHEMBL2851129 | 0.82 | KMT2A (0.58) | KMT2AMEN1ALDH1A1CYP26A1SMN1; SMN2 | |
| SCHEMBL7226978 | 0.81 | NPSR1 (0.51) | KMT2AMEN1ALDH1A1THRBHPGD | |
| SCHEMBL1147823 | 0.81 | NPSR1 (0.51) | KMT2AMEN1ALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252393-B1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2014-04-30 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |