SCHEMBL18239191

SCHEMBL18239191

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)c4ccccc4n4c6ccccc6c6ccc7c8c9ccccc9ccc8n5c7c64)cc3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 2/20 0.38
TSPO P30536 1/20 0.35
NPY5R Q15761 2/20 0.33
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
ATM Q13315 1/20 0.32
MAOB P27338 1/20 0.31
NR3C1 P04150 1/20 0.31
PLG P00747 1/20 0.31
PLAU P00749 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18239195 1.00 PTGES (0.38) PTGESTSPONPY5RMAPTNPC1
SCHEMBL18239143 0.96 PTGES (0.39) PTGESTSPONPY5RMAPTNPC1
SCHEMBL20200155 0.96 PTGES (0.39) PTGESTSPONPY5RMAPTNPC1
SCHEMBL20200154 0.95 PTGES (0.37) PTGESTSPONPY5RMAPTNPC1
SCHEMBL20200151 0.95 PTGES (0.37) PTGESTSPONPY5RMAPTNPC1
SCHEMBL20200148 0.95 PTGES (0.39) PTGESTSPONPY5RMAPTNPC1
SCHEMBL18239080 0.90 TSPO (0.40) TSPONPY5RMAPTLMNAMEN1
SCHEMBL21718134 0.86 PTGES (0.35) PTGESTSPOMAPTNPC1LMNA
SCHEMBL22858105 0.86 PTGES (0.35) PTGESTSPOMAPTNPC1LMNA
SCHEMBL20200141 0.86 MEN1 (0.39) TSPONPY5RMAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180151809-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-05-31 US disclosed
US-20180151809-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-05-31 US disclosed
WO-2016182186-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180151809-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, OPA1, MT-ND4 PTGES 1925/4885TSPO 1157/4885NPY5R 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.