Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20186942 | 0.77 | LPL (0.39) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL29856116 | 0.77 | LPL (0.39) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL20186944 | 0.77 | LIPG (0.41) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL24450016 | 0.72 | HIF1A (0.38) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL30153711 | 0.72 | LIPG (0.50) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL4825950 | 0.72 | LIPG (0.50) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL14822525 | 0.69 | LPL (0.44) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL31153 | 0.69 | GPR3 (0.48) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL21816655 | 0.69 | IRAK4 (0.41) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL22923019 | 0.69 | LPL (0.46) | LPLLIPGIRAK4PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016180536-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2016-11-17 | — | — | WO | disclosed |