Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | STAT5A | P42229 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944980 | 0.80 | JAK3 (0.41) | HTR2AHTR2CJAK3KDM4ESTAT5A | |
| SCHEMBL18239660 | 0.76 | HTR2A (0.50) | HTR2AHTR2CJAK3KDM4ERECQL | |
| SCHEMBL18202155 | 0.71 | HTR2A (0.51) | HTR2AHTR2CKDM4ERECQLSIGMAR1 | |
| SCHEMBL21028284 | 0.69 | HTR2A (0.46) | HTR2AHTR2CSIGMAR1PTGDRPTGDR2 | |
| SCHEMBL18239591 | 0.69 | JAK3 (0.37) | JAK3STAT5AZAP70SYKPTGDR2 | |
| SCHEMBL24141360 | 0.66 | PTGDR2 (0.45) | HTR2AHTR2CSIGMAR1PTGDRPTGDR2 | |
| SCHEMBL1104626 | 0.66 | HTR2A (0.66) | HTR2AHTR2CKDM4ERECQLSIGMAR1 | |
| SCHEMBL30749787 | 0.66 | HTR2A (0.66) | HTR2AHTR2CKDM4ERECQLSIGMAR1 | |
| SCHEMBL10676528 | 0.66 | KDM4E (0.44) | HTR2AHTR2CJAK3KDM4ERECQL | |
| SCHEMBL14571488 | 0.65 | PRKCB (0.54) | HTR2AHTR2CRECQLSIGMAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183278-A1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | ARIAD PHARMACEUTICALS, INC. (US) | 2016-11-17 | — | — | WO | disclosed |