Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824742 | 0.76 | KDM4E (0.37) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL1823085 | 0.75 | GABRP (0.46) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL1825469 | 0.75 | KDM4E (0.34) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL15373686 | 0.74 | KDM4E (0.38) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL354152 | 0.74 | NNMT (0.45) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL1822851 | 0.74 | KDM4E (0.40) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL1822852 | 0.74 | GABRP (0.45) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL15489015 | 0.71 | KDM4E (0.33) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL1825209 | 0.70 | MAPT (0.39) | MAPTHSP90AA1HTTSMN1; SMN2KDM4E | |
| SCHEMBL15489014 | 0.70 | KDM4E (0.31) | KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927458-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8658798-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2013-11-07 | — | — | US | disclosed |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| EP-2185536-B1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-05-04 | — | — | EP | disclosed |
| CN-101809013-A | herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG | 2010-08-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | MAPT 2616/4885HSP90AA1 480/4885HTT 719/4885 |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | MAPT 2532/4885HSP90AA1 617/4885HTT 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.