Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | CCKAR | P32238 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240666 | 1.00 | GAA (0.41) | GAANPC1RAB9ARELASMN1; SMN2 | |
| SCHEMBL18240662 | 1.00 | GAA (0.41) | GAANPC1RAB9ARELASMN1; SMN2 | |
| SCHEMBL18240624 | 0.91 | ACHE (0.46) | GAANPC1RAB9AACP3MEN1 | |
| SCHEMBL18240625 | 0.91 | ACHE (0.46) | GAANPC1RAB9AACP3MEN1 | |
| SCHEMBL18240627 | 0.91 | ACHE (0.46) | GAANPC1RAB9AACP3MEN1 | |
| SCHEMBL18240605 | 0.88 | ACP3 (0.41) | GAASMN1; SMN2TP53ACP3ALDH1A1 | |
| SCHEMBL18240604 | 0.88 | ACP3 (0.41) | GAASMN1; SMN2TP53ACP3ALDH1A1 | |
| SCHEMBL18240602 | 0.88 | ACP3 (0.41) | GAASMN1; SMN2TP53ACP3ALDH1A1 | |
| SCHEMBL18240644 | 0.88 | ACP3 (0.51) | GAANPC1RAB9ATP53ACP3 | |
| SCHEMBL18240641 | 0.88 | ACP3 (0.51) | GAANPC1RAB9ATP53ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906970-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS WITH REDUCED TACK | NOVARTIS AG (CH) | 2016-11-23 | — | — | EP | claimed |