Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240604 | 1.00 | ACP3 (0.41) | ACP3LMNASMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL18240605 | 1.00 | ACP3 (0.41) | ACP3LMNASMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL18240631 | 0.94 | ACP3 (0.45) | ACP3LMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL18240628 | 0.94 | ACP3 (0.45) | ACP3LMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL18240657 | 0.89 | LMNA (0.46) | LMNASMN1; SMN2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL18240656 | 0.89 | LMNA (0.46) | LMNASMN1; SMN2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL18240669 | 0.89 | TRPM8 (0.43) | ACP3LMNAALDH1A1 | |
| SCHEMBL18240667 | 0.89 | TRPM8 (0.43) | ACP3LMNAALDH1A1 | |
| SCHEMBL18240664 | 0.88 | GAA (0.41) | ACP3LMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL18240659 | 0.88 | ALDH1A1 (0.39) | ACP3LMNASMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906970-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS WITH REDUCED TACK | NOVARTIS AG (CH) | 2016-11-23 | — | — | EP | claimed |