Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240667 | 1.00 | TRPM8 (0.43) | TRPM8S1PR1S1PR3S1PR5ACP3 | |
| SCHEMBL18240616 | 0.92 | ACP3 (0.41) | TRPM8S1PR1S1PR3ACP3MEN1 | |
| SCHEMBL18240618 | 0.92 | ACP3 (0.41) | TRPM8S1PR1S1PR3ACP3MEN1 | |
| SCHEMBL18240782 | 0.90 | TRPM8 (0.43) | TRPM8S1PR1S1PR3ACP3MEN1 | |
| SCHEMBL18240783 | 0.90 | TRPM8 (0.43) | TRPM8S1PR1S1PR3ACP3MEN1 | |
| SCHEMBL18240602 | 0.89 | ACP3 (0.41) | ACP3ALDH1A1LMNA | |
| SCHEMBL18240605 | 0.89 | ACP3 (0.41) | ACP3ALDH1A1LMNA | |
| SCHEMBL18240604 | 0.89 | ACP3 (0.41) | ACP3ALDH1A1LMNA | |
| SCHEMBL18240691 | 0.88 | SLC6A9 (0.42) | TRPM8ACP3OPRM1OPRD1OPRK1 | |
| SCHEMBL18240693 | 0.88 | SLC6A9 (0.42) | TRPM8ACP3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906970-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS WITH REDUCED TACK | NOVARTIS AG (CH) | 2016-11-23 | — | — | EP | claimed |