Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 12/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718227 | 0.99 | PRKCA (0.46) | PRKCADGKADNM1PRKCD | |
| SCHEMBL2715800 | 0.88 | PRKCA (0.59) | PRKCADGKAPRKCD | |
| SCHEMBL13104063 | 0.81 | PRKCA (0.46) | PRKCADGKADNM1PRKCD | |
| SCHEMBL5807263 | 0.74 | HPGD (0.36) | PRKCA | |
| SCHEMBL3663826 | 0.70 | DGKA (0.74) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL3658938 | 0.70 | DGKA (0.74) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL3652144 | 0.70 | DGKA (0.74) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL3656310 | 0.70 | DGKA (0.74) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL15987674 | 0.70 | DGKA (0.87) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL813169 | 0.70 | DGKA (0.87) | DGKADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402955-B1 | Chemical defunctionalization of polymeric alkylenedioxyheterocyclics - the monomers | UNIV FLORIDA (US) | 2013-07-03 | — | — | EP | disclosed |
| EP-1979916-B1 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | UNIV FLORIDA (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2402955-A1 | Chemical defunctionalization of polymeric alkylenedioxyheterocyclics - the monomers | University of Florida Research Foundation, Incorporated (US) | 2012-01-04 | — | — | EP | disclosed |
| US-7807758-B2 | Chemical defunctionalization of polymeric alkylenedioxyheterocyclics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090221763-A1 | Chemical Defunctionalization of Polymeric Alkylenedioxyheterocyclics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221763-A1 | Chemical Defunctionalization of Polymeric Alkylenedioxyheterocyclics | DDT, STAT3, PTPN22 | PRKCA 40/4885DGKA 121/4885DNM1 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.