Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759842 | 0.81 | HTR1B (0.39) | KCNA3TDP1LMNAALDH1A1DRD2 | |
| SCHEMBL6688939 | 0.80 | KDM4E (0.58) | MEN1KMT2AALDH1A1DRD2DRD4 | |
| SCHEMBL2474020 | 0.80 | KDM4E (0.60) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5562491 | 0.80 | ATF4 (0.54) | FOXM1 | |
| SCHEMBL2473347 | 0.78 | KMT2A (0.48) | MEN1KMT2ALMNADRD2DRD4 | |
| SCHEMBL2668605 | 0.73 | KDM4E (0.56) | MEN1KMT2ATDP1LMNAFOXM1 | |
| SCHEMBL8218962 | 0.73 | KDM4E (0.53) | MEN1KMT2ARAB9ATDP1FOXM1 | |
| SCHEMBL12204045 | 0.73 | KDM4E (0.56) | MEN1KMT2ATDP1LMNAFOXM1 | |
| SCHEMBL6689983 | 0.73 | MEN1 (0.61) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9071936 | 0.72 | KDM4E (0.57) | MEN1KMT2ATDP1ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761509-B1 | SUBSTITUTED CYCLOALKYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-1761509-A2 | SUBSTITUTED CYCLOALKYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005111002-A2 | SUBSTITUTED CYCLOALKYL DERIVATIVES FOR USE IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |
| EP-1595873-A1 | Substituted cycloalkyl derivatives for the treatment of respiratory diseases | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-11-16 | — | — | EP | disclosed |