Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469303 | 0.83 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1GLAKDM4E | |
| SCHEMBL5561917 | 0.80 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL1238758 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL12204698 | 0.74 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1KDM4EHTR1A | |
| SCHEMBL1824874 | 0.73 | MEN1 (0.43) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL24631803 | 0.72 | DRD2 (0.47) | MEN1KMT2AALDH1A1GLAKDM4E | |
| SCHEMBL256797 | 0.72 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1GLAKDM4E | |
| SCHEMBL10066572 | 0.72 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1GLAKDM4E | |
| SCHEMBL6688939 | 0.70 | KDM4E (0.58) | MEN1KMT2AALDH1A1KDM4ECYP2D6 | |
| SCHEMBL2471205 | 0.70 | KMT2A (0.50) | MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004105762-A1 | MEDICAL USE OF DIAZABICYCLONONENE DERIVATIVES AS INHIBITORS OF PARASITE ASPARTIC PROTEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2004-12-09 | — | — | WO | disclosed |