Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160043 | 0.97 | KDM4E (0.48) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1004702 | 0.91 | HRH3 (0.45) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1392811 | 0.81 | HRH4 (0.51) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL24851409 | 0.79 | HRH4 (0.50) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL22509467 | 0.79 | HRH4 (0.50) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL21310107 | 0.79 | HRH4 (0.50) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL17575660 | 0.79 | HRH4 (0.50) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL1004793 | 0.78 | HRH4 (0.48) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL14916104 | 0.77 | ALDH1A1 (0.40) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL24374824 | 0.77 | HRH3 (0.40) | KDM4EMAPTSMN1; SMN2L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410164-B2 | Heterocyclic compounds and medical use thereof | FONDAZIONE TELETHON (IT) | 2025-09-09 | — | — | US | disclosed |
| WO-2016185348-A1 | 4,5,6,9-TETRAHYDROPYRROLO[2',3':3,4]CYCLOHEPTA[1,2-D] ISOXAZOLE, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS ANTITUMOR AGENTS | UNIVERSITA' DEGLI STUDI DI PALERMO (IT) | 2016-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410164-B2 | Heterocyclic compounds and medical use thereof | NPPA, NPR1, CYC1 | KDM4E 4181/4885MAPT 3586/4885SMN1; SMN2 3292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.