Sugi Predict

Sugi Predict / Compounds / SCHEMBL18252589

SCHEMBL18252589

SCHEMBL18252589

c1ccc2c(c1)-c1ccccc1-c1ccc(-c3ccc4sc5ccc(-n6c7ccccc7c7ccccc76)cc5c4c3)cc1-c1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 2/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ MEN1 O00255 1/20 0.34
▸ APAF1 O14727 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ XBP1 P17861 1/20 0.34
▸ PTBP1 P26599 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ GALK1 P51570 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ SMAD3 P84022 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ GPR3 P46089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18252540 0.95 GPR3 (0.37) ATML3MBTL1KDM4EMEN1APAF1
SCHEMBL18252524 0.95 GPR3 (0.37) ATML3MBTL1KDM4EMEN1APAF1
SCHEMBL27253925 0.91 KDM4E (0.46) ATML3MBTL1KDM4ENPC1MAPT
SCHEMBL10348594 0.91 KDM4E (0.46) ATML3MBTL1KDM4ENPC1MAPT
SCHEMBL15781004 0.91 KDM4E (0.46) ATML3MBTL1KDM4ENPC1MAPT
SCHEMBL18252573 0.91 GPR3 (0.36) ATML3MBTL1KDM4EMAPTRAB9A
SCHEMBL15965721 0.90 KDM4E (0.42) ATML3MBTL1KDM4EMAPTRAB9A
SCHEMBL10041345 0.90 KDM4E (0.44) ATML3MBTL1KDM4EMAPTRAB9A
SCHEMBL18252587 0.89 L3MBTL1 (0.47) ATML3MBTL1KDM4EMEN1APAF1
SCHEMBL18252435 0.88 GPR3 (0.36) ATML3MBTL1KDM4EMEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10256411-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-04-09 — — US disclosed
US-20170077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-03-16 — — US disclosed
US-20170077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-03-16 — — US disclosed
US-20160343951-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-11-24 — — US disclosed
US-20160343951-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160343951-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBPL8 ATM 4208/4885L3MBTL1 953/4885KDM4E 4543/4885
US-20170077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBPL8 ATM 4208/4885L3MBTL1 953/4885KDM4E 4543/4885
US-10256411-B2 Organic electroluminescent materials and devices OSBP, OSBPL3, OSBPL8 ATM 4208/4885L3MBTL1 953/4885KDM4E 4543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.