Sugi Predict

Sugi Predict / Compounds / SCHEMBL18252540

SCHEMBL18252540

SCHEMBL18252540

c1ccc2c(c1)-c1ccccc1-c1cc(-c3ccc4sc5ccccc5c4c3)ccc1-c1cc(-n3c4ccccc4c4ccccc43)ccc1-2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 1/20 0.37
▸ L3MBTL1 Q9Y468 3/20 0.37
▸ ATM Q13315 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ ALOX5 P09917 1/20 0.35
▸ MAPT P10636 4/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ APAF1 O14727 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ XBP1 P17861 1/20 0.33
▸ PTBP1 P26599 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ GALK1 P51570 1/20 0.33
▸ BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18252524 1.00 GPR3 (0.37) GPR3L3MBTL1ATMKDM4EALOX5
SCHEMBL18252573 0.96 GPR3 (0.36) GPR3L3MBTL1ATMKDM4EALOX5
SCHEMBL18252589 0.95 ATM (0.39) GPR3L3MBTL1ATMKDM4EALOX5
SCHEMBL18252435 0.91 GPR3 (0.36) GPR3L3MBTL1ATMKDM4EALOX5
SCHEMBL18252543 0.90 L3MBTL1 (0.45) GPR3L3MBTL1ATMKDM4EALOX5
SCHEMBL18252532 0.90 L3MBTL1 (0.45) GPR3L3MBTL1ATMKDM4EALOX5
SCHEMBL18589741 0.88 CYP1A2 (0.30) CYP1A2
SCHEMBL18252440 0.88 ATM (0.43) GPR3L3MBTL1ATMKDM4EALOX5
SCHEMBL17953799 0.88 ALDH1A1 (0.33) L3MBTL1ATMKDM4EALOX5ALDH1A1
SCHEMBL18252583 0.87 L3MBTL1 (0.40) GPR3L3MBTL1ATMKDM4EALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10256411-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-04-09 — — US disclosed
US-20170077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-03-16 — — US disclosed
US-20170077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-03-16 — — US disclosed
US-20160343951-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-11-24 — — US disclosed
US-20160343951-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160343951-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBPL8 GPR3 1244/4885L3MBTL1 953/4885ATM 4208/4885
US-20170077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBPL8 GPR3 1244/4885L3MBTL1 953/4885ATM 4208/4885
US-10256411-B2 Organic electroluminescent materials and devices OSBP, OSBPL3, OSBPL8 GPR3 1244/4885L3MBTL1 953/4885ATM 4208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.