SCHEMBL18253256

SCHEMBL18253256

c1ccc(-c2cc(-c3cccc(-c4cccc(N(c5ccccc5)c5ccccc5)c4)c3)ncn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 6/20 0.50
ASIC3 Q9UHC3 2/20 0.47
MIF P14174 1/20 0.47
KMT2A Q03164 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 1/20 0.40
RECQL P46063 1/20 0.40
MAPT P10636 3/20 0.39
TP53 P04637 2/20 0.39
HRH4 Q9H3N8 1/20 0.38
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18253264 0.97 ASIC3 (0.50) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL18253263 0.93 ASIC3 (0.47) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL18253257 0.92 KMO (0.53) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL18253261 0.86 ASIC3 (0.53) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL18253259 0.84 ASIC3 (0.52) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL17775601 0.84 KMO (0.66) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL19781957 0.82 KMO (0.64) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL2127493 0.82 KMO (0.68) KMOASIC3MIFKMT2ASMN1; SMN2
SCHEMBL13854537 0.82 ALDH1A1 (0.46) KMOKMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL9886709 0.82 ALDH1A1 (0.46) KMOKMT2ACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029114-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-12029114-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-02 US disclosed
US-20210104677-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-04-08 US disclosed
US-10868256-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-12-15 US disclosed
US-20160343954-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-24 US disclosed
US-20160343954-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-24 US disclosed