⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825784 | 0.84 | KCNJ1 (0.48) | — | |
| SCHEMBL25403478 | 0.75 | — | — | |
| SCHEMBL11866097 | 0.74 | — | — | |
| SCHEMBL9797693 | 0.72 | KCNJ1 (0.41) | — | |
| SCHEMBL16264160 | 0.72 | HSD11B1 (0.39) | — | |
| SCHEMBL1913986 | 0.70 | — | — | |
| SCHEMBL5040448 | 0.70 | — | — | |
| SCHEMBL360899 | 0.70 | — | — | |
| SCHEMBL14941176 | 0.70 | — | — | |
| SCHEMBL1206325 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108721295-B | Treatment of pulmonary and other disorders | 高等教育联邦系统-匹兹堡大学 | 2021-05-04 | — | — | CN | disclosed |
| EP-2994464-B1 | TREATMENT OF PULMONARY AND OTHER CONDITIONS | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2020-12-09 | — | — | EP | disclosed |
| US-10167265-B2 | Treatment of pulmonary and other conditions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180086723-A1 | TREATMENT OF PULMONARY AND OTHER CONDITIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-03-29 | — | — | US | disclosed |
| US-9862690-B2 | Treatment of pulmonary and other conditions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2018-01-09 | — | — | US | disclosed |
| US-20160090366-A1 | TREATMENT OF PULMONARY AND OTHER CONDITIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-03-31 | — | — | US | disclosed |
| EP-2994464-A2 | TREATMENT OF PULMONARY AND OTHER CONDITIONS | University of Pittsburgh - Of the Commonwealth System of Higher Education (US) | 2016-03-16 | — | — | EP | disclosed |
| WO-2014183068-A2 | TREATMENT OF PULMONARY AND OTHER CONDITIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-11-13 | — | — | WO | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |