SCHEMBL18258696

SCHEMBL18258696

COc1ccc(-c2nc3ccc(Cl)cc3c(=O)[nH]2)c(O)c1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GUSB P08236 5/20 0.61
AMY1A P0DUB6 1/20 0.53
KDM4E B2RXH2 3/20 0.52
LMNA P02545 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TNKS O95271 2/20 0.52
PARP1 P09874 2/20 0.52
TNKS2 Q9H2K2 2/20 0.52
NPC1 O15118 1/20 0.46
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
HPGD P15428 1/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18258703 0.87 GUSB (0.60) GUSBAMY1AKDM4ETNKSPARP1
SCHEMBL31066915 0.87 GUSB (0.60) GUSBAMY1AKDM4ETNKSPARP1
SCHEMBL296222 0.86 GUSB (0.56) GUSBAMY1AKDM4ETNKSPARP1
SCHEMBL16018013 0.84 GUSB (0.84) GUSBKDM4ELMNAHSD17B10TNKS
SCHEMBL29890298 0.83 GUSB (0.59) GUSBAMY1AKDM4ETNKSPARP1
SCHEMBL2370223 0.83 GUSB (0.59) GUSBAMY1AKDM4ETNKSPARP1
SCHEMBL13953178 0.83 AMY1A (0.57) GUSBAMY1AKDM4ETNKSPARP1
SCHEMBL11243512 0.81 GUSB (0.70) GUSBKDM4EHSD17B10TNKSPARP1
Phosphoric Acid SCHEMBL3658256 0.79 GUSB (0.54) GUSBAMY1AKDM4ETNKSPARP1
Phosphoric Acid SCHEMBL3660040 0.78 GUSB (0.53) GUSBAMY1AKDM4ETNKSPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US disclosed
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US disclosed
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US disclosed
EP-3098284-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME Nano CMS Co., Ltd. (KR) 2016-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME SUN2, TYR, SQLE GUSB 1639/4885AMY1A 2575/4885KDM4E 1890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.