Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 18/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18268310 | 1.00 | CHRM3 (0.50) | CHRM3CTSSCTSK | |
| SCHEMBL18261794 | 0.95 | CTSK (0.50) | CHRM3CTSSCTSK | |
| SCHEMBL18260391 | 0.94 | CHRNB2 (0.49) | CHRM3CTSSCTSK | |
| SCHEMBL18268321 | 0.94 | CHRNB2 (0.49) | CHRM3CTSSCTSK | |
| SCHEMBL18268319 | 0.92 | CTSK (0.52) | CHRM3CTSSCTSK | |
| SCHEMBL18268314 | 0.87 | CTSS (0.45) | CHRM3CTSSCTSK | |
| SCHEMBL18268312 | 0.86 | CTSK (0.48) | CHRM3CTSSCTSK | |
| SCHEMBL18268313 | 0.86 | CTSK (0.48) | CHRM3CTSSCTSK | |
| SCHEMBL18268325 | 0.85 | CTSK (0.47) | CHRM3CTSSCTSK | |
| SCHEMBL18268323 | 0.85 | CTSK (0.47) | CHRM3CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303328-B1 | AMINOESTER DERIVATIVES | CHIESI FARM SPA (IT) | 2019-03-20 | — | — | EP | disclosed |
| EP-3303328-B1 | AMINOESTER DERIVATIVES | CHIESI FARM SPA (IT) | 2019-03-20 | — | — | EP | disclosed |
| EP-3303328-A1 | AMINOESTER DERIVATIVES | Chiesi Farmaceutici S.p.A. (IT) | 2018-04-11 | — | — | EP | disclosed |
| US-9636336-B2 | Aminoester derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-05-02 | — | — | US | disclosed |
| US-9636336-B2 | Aminoester derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-05-02 | — | — | US | disclosed |
| US-9636336-B2 | Aminoester derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-05-02 | — | — | US | disclosed |
| WO-2016193244-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016193244-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-12-08 | — | — | WO | disclosed |
| US-20160346268-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-12-01 | — | — | US | disclosed |
| US-20160346268-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-12-01 | — | — | US | disclosed |
| US-20160346268-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346268-A1 | AMINOESTER DERIVATIVES | PDE4A, PDE4B, PDE3B | CHRM3 8/4885CTSS 2198/4885CTSK 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.