SCHEMBL18262004

SCHEMBL18262004

O=C(NC/C=C/CNC(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
POLB P06746 1/20 0.54
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CA2 P00918 3/20 0.46
CA3 P07451 2/20 0.46
CA5A P35218 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA7 P43166 1/20 0.46
EPHX1 P07099 1/20 0.43
EPHX2 P34913 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18262005 1.00 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL17268409 0.89 EPHX1 (0.46) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL3180746 0.86 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL9431459 0.86 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL3180753 0.86 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL9431466 0.86 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL19169987 0.84 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL9340830 0.82 CA3 (0.56) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL8975318 0.81 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL8975320 0.81 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10563009-B2 Process to produce a polyolefin reactive telechelic pre-polymer DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-18 US disclosed
US-20180162998-A1 A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-14 US disclosed
US-20180134840-A1 PROCESS TO PRODUCE A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-17 US disclosed
EP-3303443-A1 A PROCESS TO PRODUCE A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER Dow Global Technologies LLC (US) 2018-04-11 EP disclosed
EP-3303442-A1 A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER Dow Global Technologies LLC (US) 2018-04-11 EP disclosed
WO-2016191688-A1 A PROCESS TO PRODUCE A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-01 WO disclosed
WO-2016191692-A1 A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-01 WO disclosed