Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975318 | 1.00 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18262004 | 0.81 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18262005 | 0.81 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9431466 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9431459 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17268409 | 0.76 | EPHX1 (0.46) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28564887 | 0.75 | CYP2D6 (0.44) | ALDH1A1POLBKISS1R | |
| SCHEMBL10271811 | 0.75 | KISS1R (0.40) | ALDH1A1KISS1R | |
| SCHEMBL3180753 | 0.74 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2611673 | 0.74 | KISS1R (0.35) | ALDH1A1KMT2AKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506345-A | ANTIHYPOXIC AGENTS | AMERSHAM INTERNATIONAL PLC (GB) | 1996-04-09 | — | — | US | disclosed |
| US-5387692-A | A bisamine oxime compound containing a 2-nitroimidazole group | AMERSHAM INTERNATIONAL PLC (GB) | 1995-02-07 | — | — | US | disclosed |