Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18263044 | 0.88 | RAB9A (0.57) | HCRTR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL17444608 | 0.87 | KDM4E (0.65) | HCRTR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18941127 | 0.83 | KMT2A (0.78) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL18941063 | 0.82 | KMT2A (0.64) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL18941101 | 0.82 | HCRTR1 (0.73) | HCRTR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18941145 | 0.82 | RAB9A (0.66) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL18941186 | 0.80 | MAPT (0.72) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL2436534 | 0.79 | L3MBTL1 (0.65) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL18941144 | 0.79 | KMT2A (0.59) | KMT2AMEN1RAB9ANPC1HPGD | |
| SCHEMBL17444599 | 0.79 | HCRTR1 (0.54) | HCRTR1KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187667-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | NOVOGEN LIMITED (AU) | 2016-12-01 | — | — | WO | disclosed |