Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521860 | 0.94 | AKR1C3 (0.68) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR | |
| SCHEMBL5558318 | 0.93 | SMN1; SMN2 (0.66) | L3MBTL1SMN1; SMN2TP53TSHRRAB9A | |
| SCHEMBL883130 | 0.93 | TNKS (0.60) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR | |
| SCHEMBL25620305 | 0.93 | MEN1 (0.59) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR | |
| SCHEMBL3510175 | 0.91 | ESR1 (0.65) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR | |
| SCHEMBL14217726 | 0.90 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR | |
| SCHEMBL4939679 | 0.90 | MRGPRX4 (0.66) | L3MBTL1SMN1; SMN2TP53AKR1C3LOXL2 | |
| SCHEMBL8367495 | 0.90 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR | |
| SCHEMBL12260934 | 0.88 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR | |
| SCHEMBL2266392 | 0.88 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2TP53AKR1C3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447230-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | claimed |
| US-10377765-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanhydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2019-08-13 | — | — | US | disclosed |
| US-20160369046-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | NEW JERSEY INSTITUTE OF TECHNOLOGY | 2016-12-22 | — | — | US | disclosed |
| US-9447230-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-9447230-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| EP-2548203-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | New Jersey Institute of Technology (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20110257346-A1 | Polyester Ethers Derived From Asymmetrical Monomers Based Upon Bisanydrohexitols | IOWA CORN PROMOTION BOARD (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2011116270-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160369046-A1 | NEW POLYESTER ETHERS DERIVED FROM ASYMMETRICAL MONOMERS BASED UPON BISANHYDROHEXITOLS | GNE, DCXR, DERA | L3MBTL1 1654/4885SMN1; SMN2 3870/4885TP53 3885/4885 |
| US-10377765-B2 | Polyester ethers derived from asymmetrical monomers based upon bisanhydrohexitols | DCXR, CBR1, AKR1C4 | L3MBTL1 4136/4885SMN1; SMN2 3611/4885TP53 3932/4885 |
| US-20110257346-A1 | Polyester Ethers Derived From Asymmetrical Monomers Based Upon Bisanydrohexitols | GNE, FHIT, DCXR | L3MBTL1 1781/4885SMN1; SMN2 4226/4885TP53 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.