Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18263215 | 0.82 | ELANE (0.47) | HSD17B10KMT2AMEN1CA1CA2 | |
| SCHEMBL9646427 | 0.81 | KDM4E (0.48) | HSD17B10KMT2AMEN1GAACA2 | |
| SCHEMBL18272061 | 0.76 | ELANE (0.47) | POLB | |
| SCHEMBL18263212 | 0.76 | LMNA (0.50) | HSD17B10KMT2AMEN1GAACA1 | |
| SCHEMBL30410456 | 0.76 | THRB (0.40) | HSD17B10HSD11B1KMT2AMEN1MAPT | |
| SCHEMBL5704226 | 0.75 | HSD17B10 (0.48) | HSD17B10KMT2AMEN1CA1CA2 | |
| SCHEMBL10964989 | 0.75 | KDM4E (0.36) | HSD17B10KMT2AMEN1GAACA1 | |
| SCHEMBL57099 | 0.73 | GRM4 (0.44) | HSD17B10HSD11B1KMT2AMEN1GAA | |
| SCHEMBL29549932 | 0.73 | GRM4 (0.44) | HSD17B10HSD11B1KMT2AMEN1GAA | |
| SCHEMBL9064777 | 0.73 | GRM4 (0.38) | HSD17B10KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108416-B | Preparation method of 1, 2-dicyclopropylethylphenol and optical isomer thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |