SCHEMBL1826342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4907072	1.00	MDM2 (1.00)	MDM2CYP2D6CYP3A4TP53
	SCHEMBL1822198	0.90	MDM2 (0.93)	MDM2CYP2D6CYP3A4
	SCHEMBL4907039	0.89	MDM2 (0.80)	MDM2CYP2D6CYP3A4TP53
	SCHEMBL4907041	0.89	MDM2 (0.80)	MDM2CYP2D6CYP3A4TP53
	SCHEMBL2548886	0.88	CYP2D6 (1.00)	MDM2CYP2D6CYP3A4TP53
	SCHEMBL1819470	0.88	MDM2 (1.00)	MDM2CYP2D6CYP3A4
	SCHEMBL1834743	0.86	MDM2 (0.76)	MDM2CYP2D6CYP3A4
	SCHEMBL4913469	0.86	MDM2 (0.76)	MDM2CYP2D6CYP3A4
	SCHEMBL4916112	0.86	MDM2 (1.00)	MDM2CYP2D6CYP3A4
	SCHEMBL1826794	0.85	MDM2 (1.00)	MDM2CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.