Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.87 |
| ▸ | MEN1 | O00255 | 1/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | POLB | P06746 | 1/20 | 0.87 |
| ▸ | GAA | P10253 | 1/20 | 0.87 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.87 |
| ▸ | HPGD | P15428 | 1/20 | 0.87 |
| ▸ | TSHR | P16473 | 1/20 | 0.87 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.87 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.87 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | DHFR | P00374 | 5/20 | 0.59 |
| ▸ | ATIC | P31939 | 3/20 | 0.59 |
| ▸ | GART | P22102 | 2/20 | 0.59 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.51 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.51 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Folic Acid SCHEMBL27970859 | 0.96 | TYMS (0.82) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL28212675 | 0.93 | TYMS (0.85) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29349485 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29441959 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29357550 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29624885 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL3877 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL248712 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL16492117 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL332170 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128516-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING THE THERAPEUTIC AGENTS COVALENTLY BOUND THERETO | NOVARTIS AG (CH) | 2021-05-06 | — | — | US | disclosed |
| EP-3332811-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING COVALENTLY ATTACHED CAMPTOTHECIN | Cerulean Pharma Inc. (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-2402036-B1 | Cyclodextrin-based polymers for delivering the therapeutic agents covalently attached thereto | CERULEAN PHARMA INC (US) | 2018-02-14 | — | — | EP | disclosed |
| US-20170369651-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING THE THERAPEUTIC AGENTS COVALENTLY BOUND THERETO | INSERT THERAPEUTICS, INC. | 2017-12-28 | — | — | US | disclosed |
| US-9550860-B2 | Cyclodextrin-based polymers for therapeutics delivery | CERULEAN PHARMA INC. (US) | 2017-01-24 | — | — | US | disclosed |
| US-20150165055-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING THE THERAPEUTIC AGENTS COVALENTLY BOUND THERETO | CERULEAN PHARMA INC. (US) | 2015-06-18 | — | — | US | disclosed |
| US-20140288023-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | CERULEAN PHARMA INC. (US) | 2014-09-25 | — | — | US | disclosed |
| US-8680202-B2 | Cyclodextrin-based polymers for therapeutics delivery | CERULEAN PHARMA INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20140044669-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | CERULEAN PHARMA INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-8609081-B2 | Cyclodextrin-based polymers for therapeutics delivery | CERULEAN PHARMA INC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-20090169478-A1 | In Vivo Imaging and Therapy with Magnetic Nanoparticle Conjugates | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) | 2009-07-02 | — | — | US | disclosed |
| EP-1901762-A2 | USE OF ONE OR MORE METAL CARRIERS TO SELECTIVELY KILL MAMMALIAN CELLS | Cancure Laboratories, LLC (US) | 2008-03-26 | — | — | EP | disclosed |
| US-20080058427-A1 | Cyclodextrin-based polymers for therapeutics delivery | INSERT THERAPEUTICS, INC. (US) | 2008-03-06 | — | — | US | disclosed |
| EP-1855725-A2 | CYCLODEXTRIN-BASED POLYMERS CONTAINING PHOTOCLEAVABLE LINKERS FOR DRUG DELIVERY | Insert Therapeutics Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| US-7270808-B2 | Having covalently coupled bioactive agent and targeting ligand; controlled release; stability, solubility; reduced toxicity | INSERT THERAPEUTICS, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| WO-2007008376-A2 | USE OF ONE OR MORE METAL CARRIERS TO SELECTIVELY KILL MAMMALIAN CELLS | CANCURE LABORATORIES, LLC (US) | 2007-01-18 | — | — | WO | disclosed |
| US-20070010427-A1 | Use of one or more metal carriers to selectively kill mammalian cells | CANCURE LABORATORIES, LLC (US) | 2007-01-11 | — | — | US | disclosed |
| US-20060210527-A1 | Cyclodextrin-based polymers for therapeutics delivery | INSERT THERAPEUTICS, INC. (US) | 2006-09-21 | — | — | US | disclosed |
| WO-2006089007-A2 | CYCLODEXTRIN-BASED POLYMERS CONTAINING PHOTOCLEAVABLE LINKERS FOR DRUG DELIVERY | INSERT THERAPEUTICS, INC. (US) | 2006-08-24 | — | — | WO | disclosed |
| US-20040077595-A1 | Having covalently coupled bioactive agent and targeting ligand; controlled release; stability, solubility; reduced toxicity | INSERT THERAPEUTICS, INC. (US) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058427-A1 | Cyclodextrin-based polymers for therapeutics delivery | DDOST, DSC1, SI | TYMS 1005/4885KDM4E 3582/4885MEN1 4082/4885 |
| US-20210128516-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING THE THERAPEUTIC AGENTS COVALENTLY BOUND THERETO | SDCBP, DDOST, CD47 | TYMS 1034/4885KDM4E 3113/4885MEN1 4023/4885 |
| US-20140044669-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | DDOST, DSC1, SI | TYMS 1005/4885KDM4E 3582/4885MEN1 4082/4885 |
| US-20040077595-A1 | Having covalently coupled bioactive agent and targeting ligand; controlled release; stability, solubility; reduced toxicity | CD40, TNFSF11, TNFSF10 | TYMS 3053/4885KDM4E 4241/4885MEN1 3956/4885 |
| US-20060210527-A1 | Cyclodextrin-based polymers for therapeutics delivery | SI, PAICS, DSC1 | TYMS 421/4885KDM4E 3629/4885MEN1 3718/4885 |
| US-20140288023-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | DDOST, DSC1, SI | TYMS 1005/4885KDM4E 3582/4885MEN1 4082/4885 |
| US-20150165055-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING THE THERAPEUTIC AGENTS COVALENTLY BOUND THERETO | SDCBP, DDOST, CD47 | TYMS 1034/4885KDM4E 3113/4885MEN1 4023/4885 |
| US-20170369651-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING THE THERAPEUTIC AGENTS COVALENTLY BOUND THERETO | SDCBP, DDOST, CD47 | TYMS 1034/4885KDM4E 3113/4885MEN1 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.