SCHEMBL18267240

SCHEMBL18267240

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc2c3ccc(-n4c5ccc(C(C)(C)C)cc5c5cc(C(C)(C)C)ccc54)cc3n(-c3ccc(N4c5ccccc5C(C)(C)c5ccccc54)cc3)c2c1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.31
RORA P35398 1/20 0.31
RORC P51449 1/20 0.31
RORB Q92753 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PPARG P37231 1/20 0.30
KIF11 P52732 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12333423 0.94 NPSR1 (0.34) PGRRORARORCRORBNPSR1
SCHEMBL22600916 0.91 PGR (0.32) PGRRORARORCRORBNPSR1
SCHEMBL23056677 0.87 HTR1A (0.33) PGRRORARORCRORBNPSR1
SCHEMBL23056680 0.85 P2RY1 (0.30)
SCHEMBL15788347 0.84 NPSR1 (0.30) NPSR1
SCHEMBL10134263 0.84 ALDH1A1 (0.32) NPSR1
SCHEMBL2604417 0.83 KDM4E (0.34) PPARGKIF11
SCHEMBL2604411 0.82 NPC1 (0.35) PGRRORARORCRORBKIF11
SCHEMBL23331192 0.81 KDM4E (0.47) PGRRORARORCRORBNPSR1
SCHEMBL2604397 0.81 KDM4E (0.47) PGRRORARORCRORBPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361379-B2 Photoelectric conversion element, photosensor, and imaging device FUJIFILM CORPORATION (JP) 2019-07-23 US disclosed
US-20160351830-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOSENSOR, AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed
US-20160351830-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOSENSOR, AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed