Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604665 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL17516257 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL25107536 | 0.89 | MEN1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL2606047 | 0.89 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL25605744 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL18251701 | 0.85 | CYP3A4 (0.52) | CYP3A4CYP2C19CHRM1 | |
| SCHEMBL25605709 | 0.84 | CHRM1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL24838380 | 0.84 | CHRM1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL25628460 | 0.84 | L3MBTL3 (0.47) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL12396446 | 0.84 | CYP3A4 (0.55) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278402-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| US-20160347749-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347749-A1 | DIAZEPANE DERIVATIVES AND USES THEREOF | BRDT, BRD4, BRD3 | ALDH1A1 3263/4885MEN1 1939/4885KMT2A 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.