SCHEMBL1826883

SCHEMBL1826883

CC=C(C)C([SiH3])=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.52
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.43
FBP1 P09467 2/20 0.42
DHODH Q02127 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
KDM1A O60341 1/20 0.40
RECQL P46063 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
AKR1C1 Q04828 1/20 0.36
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140742 0.77 ALDH1A1 (0.54) AKR1C3ALDH1A1TSHRHTTFBP1
SCHEMBL23458002 0.76 AKR1C3 (0.73) AKR1C3ALDH1A1TSHRHTTFBP1
SCHEMBL6433811 0.76 AKR1C3 (0.73) AKR1C3ALDH1A1TSHRHTTFBP1
SCHEMBL8072809 0.73 ALDH1A1 (0.48) AKR1C3ALDH1A1TSHRFBP1KDM1A
SCHEMBL8850430 0.72 AKR1C3 (0.88) AKR1C3ALDH1A1TSHRHTTFBP1
SCHEMBL4758975 0.72 AKR1C3 (0.60) AKR1C3ALDH1A1TSHRHTTFBP1
SCHEMBL5342048 0.72 AKR1C3 (0.67) AKR1C3ALDH1A1TSHRHTTFBP1
SCHEMBL5342051 0.72 AKR1C3 (0.67) AKR1C3ALDH1A1TSHRHTTFBP1
SCHEMBL13119929 0.72 AKR1C3 (0.60) AKR1C3ALDH1A1TSHRHTTFBP1
Acetic Acid SCHEMBL6897109 0.71 AKR1C3 (0.95) AKR1C3ALDH1A1TSHRHTTFBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US claimed
EP-1703327-B1 Composition for forming antireflection film, laminate, and method for forming resist pattern JSR CORP (JP) 2011-05-11 EP disclosed
EP-1818723-B1 COMPOSITION FOR FORMING ANTIREFLECTION FILM, LAYERED PRODUCT, AND METHOD OF FORMING RESIST PATTERN JSR CORP (JP) 2011-05-04 EP disclosed
US-7709182-B2 Composition for forming antireflection film, layered product, and method of forming resist pattern JSR CORPORATION (JP) 2010-05-04 US disclosed
US-7514205-B2 Composition for forming antireflection film, laminate, and method for forming resist pattern JSR CORPORATION (JP) 2009-04-07 US disclosed
US-20080124524-A1 Composition For Forming Antireflection Film, Layered Product, And Method Of Forming Resist Pattern JSR CORPORATION (JP) 2008-05-29 US disclosed
EP-1818723-A1 COMPOSITION FOR FORMING ANTIREFLECTION FILM, LAYERED PRODUCT, AND METHOD OF FORMING RESIST PATTERN JSR Corporation (JP) 2007-08-15 EP disclosed
US-20060223008-A1 Composition for forming antireflection film, laminate, and method for forming resist pattern JSR CORPORATION (JP) 2006-10-05 US disclosed
EP-1703327-A2 Composition for forming antireflection film, laminate, and method for forming resist pattern JSR Corporation (JP) 2006-09-20 EP disclosed
EP-0683185-B1 (Meth)acrylate copolymer and elastomer compositions comprising said copolymer SUMITOMO CHEMICAL CO (JP) 1999-03-31 EP disclosed
EP-0583918-B1 Reflection preventing film and process for forming resist pattern using the same JAPAN SYNTHETIC RUBBER CO LTD (JP) 1999-03-10 EP disclosed
US-5610226-A ELASTOMER OF COPOLYMER, CARBON BLACK AND A CROSSLINKING AGENT, AND RUBBER OBTAINED BY VULCANIZING ELASTOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-03-11 US disclosed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed
US-5410005-A Comprising acrylic amide and ester copolymers and their salts, having carboxyl and sulfonic acid groups as well as fluoro JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-04-25 US disclosed
EP-0583918-A2 Reflection preventing film and process for forming resist pattern using the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-02-23 EP disclosed
EP-0367577-B1 Novel ester group-containing (meth) acrylic acid ester, novel (co)polymer thereof, composition comprising the (co) polymer and composition comprising the ester group- containing (meth) acrylic acid ester JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-01-05 EP disclosed
US-5026807-A Heat and cold resistance; oil repellents JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-06-25 US disclosed
EP-0367577-A1 Novel ester group-containing (meth) acrylic acid ester, novel (co)polymer thereof, composition comprising the (co) polymer and composition comprising the ester group- containing (meth) acrylic acid ester JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-05-09 EP disclosed