SCHEMBL8072809

SCHEMBL8072809

[SiH3]C([SiH3])=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
AKR1C3 P42330 1/20 0.48
AKR1C1 Q04828 1/20 0.46
ESR1 P03372 1/20 0.46
FBP1 P09467 3/20 0.43
MAOB P27338 1/20 0.43
CYP2A6 P11509 1/20 0.43
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
PRMT1 Q99873 1/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MCL1 Q07820 1/20 0.40
KDM1A O60341 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18918379 0.80 MCL1 (0.45) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL140742 0.80 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL1477748 0.78 AKR1C1 (0.50) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL9087392 0.78 AKR1C1 (0.50) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL29253620 0.78 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL131223 0.78 MAOB (0.53) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL18527026 0.76 ALDH1A1 (0.56) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL23045161 0.75 ALDH1A1 (0.43) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL28375779 0.75 TSHR (0.43) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL7945245 0.75 KDM1A (0.46) ALDH1A1TSHRAKR1C3FBP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6100331-A Graft copolymer and styrene-based resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-08-08 US disclosed
EP-0860456-A1 Graft copolymer and styrene-based resin composition Idemitsu Petrochemical Co., Ltd. (JP) 1998-08-26 EP disclosed
EP-0767234-A2 (Co)polymers based on vinyl monomers and their use in electroluminescent devices BAYER AG (DE) 1997-04-09 EP disclosed