Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227644 | 0.74 | GRIN2D (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL382451 | 0.71 | NPC1 (0.35) | MAOAALDH1A1TDP1PARP1SMN1; SMN2 | |
| SCHEMBL1153218 | 0.71 | ESR1 (0.39) | MAOAMAOBALDH1A1TDP1CA9 | |
| SCHEMBL17423913 | 0.71 | HSP90AA1 (0.39) | CYP2A6CA9CA1CA2CA4 | |
| SCHEMBL3226561 | 0.71 | S100A4 (0.39) | CYP1A2ALDH1A1PARP1GAALMNA | |
| SCHEMBL7220827 | 0.71 | — | — | |
| SCHEMBL3795668 | 0.71 | TERT (0.42) | CYP2A6ALDH1A1TDP1SMN1; SMN2HSD17B10 | |
| SCHEMBL11050387 | 0.70 | MAPT (0.42) | CYP2A6ALDH1A1SMN1; SMN2GAALMNA | |
| Water SCHEMBL11162060 | 0.70 | NPC1 (0.34) | MAOAALDH1A1TDP1PARP1SMN1; SMN2 | |
| SCHEMBL1418729 | 0.68 | ALDH1A1 (0.40) | CYP2A6ALDH1A1TDP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903542-A | Method for synthesizing 5-nitro-6-methyl benzimidazolone in microchannel reactor | 常州大学 | 2023-10-20 | — | — | CN | claimed |
| CN-109627219-A | A kind of production method of 5- amino-6-methyl benzimidazolone | 高邮市华宝颜料有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-104761717-B | A kind of PAEK quadripolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2018-03-20 | — | — | CN | claimed |
| CN-104761717-A | Polyaryletherketone quadripolymer and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY | 2015-07-08 | — | — | CN | claimed |
| CN-101863840-B | Preparation method of 5-amino-6-methyl benzimidazolone | ZIBO SHENGMA CHEMICAL PLANT | 2011-11-16 | — | — | CN | claimed |
| CN-101863840-A | Preparation method of 5-amino-6-methyl benzimidazolone | ZIBO SHENGMA CHEMICAL PLANT | 2010-10-20 | — | — | CN | claimed |
| US-4374250-A | CYCLIZATION, SELENIUM CATALYST | OSAKA MUNICIPAL GOVERNMENT (JP) | 1983-02-15 | — | — | US | claimed |
| US-4367337-A | Process for conversion of benzimidazolones to benzotriazoles | THE SHERWIN-WILLIAMS COMPANY (US) | 1983-01-04 | — | — | US | claimed |
| US-4329477-A | Process for the production of 4- or 5-methyl-2-mercaptobenzimidazole | BAYER AG (DE) | 1982-05-11 | — | — | US | claimed |
| EP-0035185-A1 | Process for the preparation of 4(5)-methyl-2-mercaptobenzimidazole | BAYER AG (DE) | 1981-09-09 | — | — | EP | claimed |
| CN-116903542-A | Method for synthesizing 5-nitro-6-methyl benzimidazolone in microchannel reactor | 常州大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-116903542-A | Method for synthesizing 5-nitro-6-methyl benzimidazolone in microchannel reactor | 常州大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-111841638-B | Visible light catalyst and CO catalytic conversion thereof2Use of benzazepine for the synthesis of benzazepine | 杭州师范大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-111841638-A | Visible light catalyst and CO catalytic conversion thereof2Use of benzazepine for the synthesis of benzazepine | 杭州师范大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-109627219-A | A kind of production method of 5- amino-6-methyl benzimidazolone | 高邮市华宝颜料有限公司 | 2019-04-16 | — | — | CN | disclosed |
| US-4329477-A | Process for the production of 4- or 5-methyl-2-mercaptobenzimidazole | BAYER AG (DE) | 1982-05-11 | — | — | US | disclosed |
| US-4329477-A | Process for the production of 4- or 5-methyl-2-mercaptobenzimidazole | BAYER AG (DE) | 1982-05-11 | — | — | US | disclosed |
| EP-0035185-A1 | Process for the preparation of 4(5)-methyl-2-mercaptobenzimidazole | BAYER AG (DE) | 1981-09-09 | — | — | EP | disclosed |
| EP-0035185-A1 | Process for the preparation of 4(5)-methyl-2-mercaptobenzimidazole | BAYER AG (DE) | 1981-09-09 | — | — | EP | disclosed |
| US-3943109-A | CURING | CIBA-GEIGY CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |