Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19439578 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2CTSKHSD17B10POLB | |
| SCHEMBL28996869 | 0.85 | ZDHHC7 (0.46) | TSHRSMN1; SMN2HSD17B10POLBPOLA1 | |
| SCHEMBL2137700 | 0.83 | TSHR (0.40) | TSHRSMN1; SMN2CTSKHSD17B10POLB | |
| SCHEMBL17759039 | 0.82 | MGAM (0.41) | TSHRSMN1; SMN2CTSKHSD17B10POLB | |
| SCHEMBL17755804 | 0.82 | TSHR (0.34) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL29004671 | 0.82 | TSHR (0.44) | TSHRSMN1; SMN2CTSKPOLBPOLA1 | |
| SCHEMBL27163541 | 0.82 | ALDH1A1 (0.35) | TSHRHSD17B10POLBPOLA1HDAC7 | |
| SCHEMBL17759040 | 0.81 | LMNA (0.43) | TSHRSMN1; SMN2CTSKCHRM1AKR1A1 | |
| SCHEMBL9442266 | 0.79 | TSHR (0.48) | TSHRSMN1; SMN2POLBPOLA1MEN1 | |
| SCHEMBL17759195 | 0.79 | HDAC3 (0.40) | TSHRSMN1; SMN2CTSKHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673862-B2 | Processes to produce brivaracetam | SUZHOU PENGXU PHARMATECH CO. LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| US-20180155284-A1 | PROCESSES TO PRODUCE BRIVARACETAM | ESTEVE QUIMlCA S.A. (ES) | 2018-06-07 | — | — | US | disclosed |
| WO-2016191435-A1 | PROCESSES TO PRODUCE BRIVARACETAM | WANG PENG (US) | 2016-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673862-B2 | Processes to produce brivaracetam | BLVRB, CYP3A4, POR | TSHR 1088/4885SMN1; SMN2 4495/4885CTSK 3252/4885 |
| US-20180155284-A1 | PROCESSES TO PRODUCE BRIVARACETAM | BLVRB, CYP3A4, POR | TSHR 1088/4885SMN1; SMN2 4495/4885CTSK 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.