Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.59 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.56 |
| ▸ | KRAS | P01116 | 3/20 | 0.56 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | HINT1 | P49773 | 1/20 | 0.53 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26067682 | 0.94 | TGM2 (0.69) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL21715305 | 0.94 | TGM2 (0.69) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL21715304 | 0.94 | TGM2 (0.69) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL20850065 | 0.93 | TGM2 (0.68) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL18648315 | 0.93 | NT5E (0.71) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL23149534 | 0.93 | TGM2 (0.68) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL20850061 | 0.93 | NT5E (0.71) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL15747230 | 0.93 | TGM2 (0.68) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL2033285 | 0.93 | TGM2 (0.68) | TGM2NT5ETAS1R3TAS1R1FUT5 | |
| SCHEMBL720115 | 0.93 | TGM2 (0.68) | TGM2NT5ETAS1R3TAS1R1FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160348099-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160348099-A1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, ADAR, NSUN3 | TGM2 1916/4885NT5E 32/4885TAS1R3 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.