SCHEMBL720115

SCHEMBL720115

COC1C(O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.68
FUT5 Q11128 1/20 0.65
KRAS P01116 2/20 0.64
NT5E P21589 1/20 0.63
RNASEL Q05823 4/20 0.62
TAS1R3 Q7RTX0 1/20 0.62
TAS1R1 Q7RTX1 1/20 0.62
P2RY6 Q15077 2/20 0.60
P2RY2 P41231 1/20 0.60
P2RY4 P51582 1/20 0.60
P2RX3 P56373 3/20 0.59
ENPP1 P22413 2/20 0.59
P2RY1 P47900 2/20 0.59
P2RX1 P51575 2/20 0.59
P2RY11 Q96G91 1/20 0.59
P2RX4 Q99571 1/20 0.59
IMPDH2 P12268 1/20 0.58
IMPDH1 P20839 1/20 0.58
DCPS Q96C86 1/20 0.57
P2RY12 Q9H244 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15747230 1.00 TGM2 (0.68) TGM2FUT5KRASNT5ERNASEL
SCHEMBL2033285 1.00 TGM2 (0.68) TGM2FUT5KRASNT5ERNASEL
SCHEMBL23149534 1.00 TGM2 (0.68) TGM2FUT5KRASNT5ERNASEL
SCHEMBL20850065 1.00 TGM2 (0.68) TGM2FUT5KRASNT5ERNASEL
SCHEMBL21715304 0.99 TGM2 (0.69) TGM2FUT5KRASNT5ERNASEL
SCHEMBL26067682 0.99 TGM2 (0.69) TGM2FUT5KRASNT5ERNASEL
SCHEMBL21715305 0.99 TGM2 (0.69) TGM2FUT5KRASNT5ERNASEL
SCHEMBL21184323 0.95 TGM2 (0.68) TGM2FUT5KRASNT5ERNASEL
SCHEMBL19325472 0.95 TGM2 (0.68) TGM2FUT5KRASNT5ERNASEL
SCHEMBL18763616 0.95 TGM2 (0.68) TGM2FUT5KRASNT5ERNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4531842-A2 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION ATEA Pharmaceuticals, Inc. (US) 2025-04-09 EP disclosed
US-12263229-B2 Induction of osteogenesis by delivering BMP encoding RNA ETHRIS GMBH (DE) 2025-04-01 US disclosed
US-20250082656-A1 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION Atea Pharmaceuticals, Inc. (US) 2025-03-13 US disclosed
US-12023371-B2 Terminally modified RNA MODERNATX, INC. (US) 2024-07-02 US disclosed
WO-2024094027-A1 BLOCKING SEQUENCE, KIT THEREOF, AND METHOD FOR USING SAME 深圳鸿生生物科技有限公司 2024-05-10 WO disclosed
EP-3836903-B1 LIPID-BASED FORMULATIONS CONTAINING SALTS FOR THE DELIVERY OF RNA ETHRIS GMBH (DE) 2024-05-01 EP disclosed
WO-2023230348-A2 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION Atea Pharmaceuticals, Inc. (US) 2023-11-30 WO disclosed
EP-3784284-B1 LIPID-BASED FORMULATIONS FOR THE DELIVERY OF RNA ETHRIS GMBH (DE) 2023-08-02 EP disclosed
CN-115997033-A Catalytic control sequencing by synthetic generation of traceless DNA 伊鲁米纳公司 2023-04-21 CN disclosed
EP-4151739-A1 IMPROVED TRANSPOSON SYSTEM FOR GENE DELIVERY T-CURX GmbH (DE) 2023-03-22 EP disclosed
US-7666855-B2 2′-C-methyl nucleoside derivatives METABASIS THERAPEUTICS, INC. (US) 2010-02-23 US disclosed
US-20090118223-A1 Novel 2'-c-methyl and 4'c-methyl nucleoside derivatives MERCK SHARP & DOHME CORP. 2009-05-07 US disclosed
EP-1915053-A2 NOVEL 2'-C-METHYL AND 4'-C-METHYL NUCLEOSIDE DERIVATIVES Merck & Co., Inc. (US) 2008-04-30 EP disclosed
EP-1905778-A2 Novel 2'-C-methyl nucleoside derivatives Metabasis Therapeutics, Inc. (US) 2008-04-02 EP disclosed
US-20070179114-A1 Novel 2'-C methyl nucleoside derivatives METABASIS THERAPEUTICS, INC. (US) 2007-08-02 US disclosed
US-20070042989-A1 Novel 2'-C-methyl nucleoside derivatives METABASIS THERAPEUTICS, INC. (US) 2007-02-22 US disclosed
WO-2007022073-A2 NOVEL 2'-C-METHYL AND 4'-C-METHYL NUCLEOSIDE DERIVATIVES MERCK & CO., INC. (US) 2007-02-22 WO disclosed
EP-1720556-A2 NOVEL 2'-C-METHYL NUCLEOSIDE DERIVATIVES Merck & Co., Inc. (US) 2006-11-15 EP disclosed
WO-2005084192-A2 NOVEL 2’-C-METHYL NUCLEOSIDE DERIVATIVES MERCK & CO., INC. (US) 2005-09-15 WO disclosed
US-20050182252-A1 Hepatitis C viral infection; 2'-C-beta-methyl-7-deazaadenosine; trans-4-(aryl)-2-(4-nitrophenoxy)-2-oxo-1,3,2-dioxaphosphorinanes METABASIS THERAPEUTICS, INC. 2005-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050182252-A1 Hepatitis C viral infection; 2'-C-beta-methyl-7-deazaadenosine; trans-4-(aryl)-2-(4-nitrophenoxy)-2-oxo-1,3,2-dioxaphosphorinanes MTAP, NT5C3B, ADAR TGM2 2235/4885FUT5 300/4885KRAS 2645/4885
US-12263229-B2 Induction of osteogenesis by delivering BMP encoding RNA BMP2, BMP1, BMP6 TGM2 4109/4885FUT5 4455/4885KRAS 3796/4885
US-20070042989-A1 Novel 2'-C-methyl nucleoside derivatives NSUN2, NT5C3B, MTAP TGM2 1465/4885FUT5 77/4885KRAS 2417/4885
US-20250082656-A1 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION FCGR3B, HAVCR2, FCGR2A TGM2 4064/4885FUT5 82/4885KRAS 3897/4885
US-12023371-B2 Terminally modified RNA RNGTT, NSUN3, RNMT TGM2 3781/4885FUT5 641/4885KRAS 2697/4885
US-20090118223-A1 Novel 2'-c-methyl and 4'c-methyl nucleoside derivatives MTAP, NT5C3B, NSUN2 TGM2 1500/4885FUT5 175/4885KRAS 3197/4885
US-20070179114-A1 Novel 2'-C methyl nucleoside derivatives NSUN2, NT5C3B, MTAP TGM2 1522/4885FUT5 87/4885KRAS 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.