Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.48 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.48 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767866 | 0.88 | RNASE1 (0.44) | RNASE1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9908701 | 0.88 | RNASE1 (0.44) | RNASE1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9908703 | 0.81 | RNASE1 (0.42) | RNASE1POLBCHRM2CHRM4CHRM1 | |
| SCHEMBL15216169 | 0.81 | RNASE1 (0.40) | RNASE1POLBCHRM2CHRM4CHRM1 | |
| SCHEMBL768015 | 0.81 | RNASE1 (0.42) | RNASE1POLBCHRM2CHRM4CHRM1 | |
| SCHEMBL15216170 | 0.81 | RNASE1 (0.40) | RNASE1POLBCHRM2CHRM4CHRM1 | |
| SCHEMBL22801906 | 0.81 | UPP1 (0.43) | POLBLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL8762522 | 0.77 | LGALS9 (0.56) | RNASE1POLBLGALS9LGALS1LGALS3 | |
| SCHEMBL6298700 | 0.76 | RNASE1 (0.46) | RNASE1POLBLGALS9LGALS1LGALS3 | |
| SCHEMBL23216267 | 0.74 | LGALS9 (0.47) | RNASE1POLBLGALS9LGALS1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160348110-A1 | NUCLEIC ACID CHEMICAL MODIFICATIONS | ALNYLAM PHARMACEUTICALS INC (US) | 2016-12-01 | — | — | US | disclosed |