SCHEMBL6298700

SCHEMBL6298700

O=C(O[C@@H]1C[C@@H](CO)O[C@H]1Cl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.46
LGALS9 O00182 1/20 0.43
LGALS1 P09382 1/20 0.43
LGALS3 P17931 1/20 0.43
LGALS7; LGALS7B P47929 1/20 0.43
RAB9A P51151 2/20 0.43
CHRM2 P08172 2/20 0.43
CHRM4 P08173 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
BCHE P06276 2/20 0.42
POLB P06746 1/20 0.42
CHRNA7 P36544 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8815309 0.82 LGALS9 (0.46) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL13274766 0.77 RNASE1 (0.42) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL13274194 0.77 RNASE1 (0.42) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL18271850 0.76 RNASE1 (0.53) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL8811566 0.75 LGALS9 (0.47) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL8811557 0.75 LGALS9 (0.50) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL8811559 0.75 LGALS9 (0.47) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL19020474 0.75 RNASE1 (0.43) RNASE1LGALS9LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL9469882 0.75 LGALS9 (0.46) LGALS9LGALS1LGALS3LGALS7; LGALS7BRAB9A
SCHEMBL13396710 0.73 RNASE1 (0.52) RNASE1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6884880-B2 Process for the preparation of 9-β-anomeric nucleoside analogs ASH STEVENS, INC. (US) 2005-04-26 US disclosed
US-20040039190-A1 Process for the preparation of 9-beta-anomeric nucleoside analogs ASH STEVENS, INC. 2004-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039190-A1 Process for the preparation of 9-beta-anomeric nucleoside analogs DPYD, SLC29A2, GALE RNASE1 426/4885LGALS9 367/4885LGALS1 1135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.