Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.37 |
| ▸ | ECE1 | P42892 | 4/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688082 | 0.84 | ECE1 (0.40) | ECE1PDCD1LG2CD274MMP2MMP9 | |
| SCHEMBL14829839 | 0.84 | ECE1 (0.47) | BMP1ECE1PDCD1LG2CD274MMP8 | |
| SCHEMBL17178036 | 0.82 | BMP1 (0.42) | BMP1MMP2MMP1 | |
| SCHEMBL3856802 | 0.81 | ECE1 (0.42) | ECE1PDCD1LG2CD274 | |
| SCHEMBL8229032 | 0.81 | ECE1 (0.40) | BMP1ECE1PDCD1LG2CD274MMP2 | |
| SCHEMBL7034111 | 0.81 | ECE1 (0.42) | ECE1PDCD1LG2CD274 | |
| SCHEMBL25556364 | 0.81 | ECE1 (0.40) | BMP1ECE1PDCD1LG2CD274MMP2 | |
| SCHEMBL22652002 | 0.81 | GGT1 (0.39) | BMP1ECE1MMP2MMP9MMP8 | |
| SCHEMBL14112002 | 0.79 | ECE1 (0.39) | ECE1MMP2MMP9MMP1 | |
| SCHEMBL30406637 | 0.79 | ECE1 (0.46) | ECE1PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160349269-A1 | COMPOSITIONS AND METHODS FOR ANALYSIS OF PROTEIN SEQUENCES AND POST-TRANSLATIONAL MODIFICATIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-01 | — | — | US | disclosed |